The answer to the life, the universe, and Davao being in the middle of a game? Purpliser game 42 with LEAH!

Game 42 begins with these 24 amounts...

1p
10p
50p
£1
£5
£10
£25
£50
£100
£250
£500
£750
£1,000
£3,000
£5,000
£10,000
£15,000
£20,000
£35,000
£50,000
£75,000
£100,000
£150,000
£250,000

...that is, until we start moving things around once again with that Dulux Purpliser. Pick five reds, five blues, and five greens - all 1-12. Then it'll be time to manipulate them!

Reds: 8, 6, 2, 4, 3
Blues: 1, 5, 9, 10, 12
Greens: 8, 5, 3, 12, 2

I'll apply them in the order they're found, the random board is a little more challenging to me

Going OLD SCHOOL and taking the control of the board out of the equation... the Banker will surely be surprised by this, but let's see what it's left you, huh?

Those reds: £50,000, £5,000, £15,000, £150,000, £1,000
The blues: 10p, £25, £750, £10, 1p
The greens: 15%, 10%, 40%, 5%, 20%

The new board, then:

£200.01
£7,500.10
50p
£1
£5
£7,510
£525
£50
£100
£250
£500
£6,750
£800
£3,000
£4,500
£10,000
£9,000
£20,000
£35,000
£42,500
£75,000
£100,000
£142,500
£250,000

As adorable as you'd expect from a Purpliser, then. Box 1 is on the table and five of the 23 lowest integers above that one will comprise this first round. GAME ON!

Let's start with 6, 4, 12, 19, 9.

And we're away!

Box 6 - £7,500.10, just because even this application of the Purpliser was apparently too much.

Box 4 - £4,500 continues that theme...

Box 12 - £20,000... hmm. True blue time?

Box 19 - £500! Evidently so!

Box 9 - £100! You can't complain about that start!

It's prediction time on this 19-box...

£200.01
50p
£1
£5
£7,510
£525
£50
£250
£6,750
£800
£3,000
£10,000
£9,000
£35,000
£42,500
£75,000
£100,000
£142,500
£250,000

The Banker is still surprised by what you did, but is he going to be textbook with his opening offer? You make the prediction and we'll find out...

PLAYER'S PREDICTION

£10,000

Textbook, you say?

Well, it's not that.

BANKER'S OFFER

£9,500

Not that it's far off, mind!

BOX 25 MONEY MENU
15%
65%
115%
165%
215%
315%

Clearly a good start with the prediction! To confirm, at £9,500, Deal or No Deal?

Awesome, good start on the board and a good start on 23

I find with the purpliser, everyone either focuses on moving as much money as possible in the interests of stability, or as little money as possible in the interest of preserving the top prizes. Where's the fun in that?

Anyway, NO DEAL! Boxes 3, 7, 22, and 8 next.

Not a fan of a focused strategy apparently

Box 3 - £75,000! I think we can all tell that's not the box you'd prefer to pick.

Box 7 - £7,510 is the other "chunky" Purplised blue...

Box 22 - £9,000 was the one red to get a big chunk out of it, conversely!

Box 8 - £250,000! Ugh.

The Banker will obviously be pleased...

£200.01
50p
£1
£5
£525
£50
£250
£6,750
£800
£3,000
£10,000
£35,000
£42,500
£100,000
£142,500

...but with some sizable sums still surviving, what will the offer be?

I'm glad there's a £150k on this board.

PLAYER'S PREDICTION

£5,500

BANKER'S OFFER

£8,000

Oh.

BOX 25 MONEY MENU
15%
65%
115%
165%
215%
315%
-£11,000

That 31% miss came with painful consequences, but at £8,000, Deal or No Deal?

...oh.
Well okay then.
I was expecting a lot more punishment, clearly
Still, I'm not about to take a defeatist second offer. NO DEAL, with Boxes 14, 20, 21 and 10 next.

Box 14 - £100,000! This might be the most... defeat-est run of boxes we've seen in a while...

Box 20 - £525, good, let's not use spoiler boxes it can't be that bad already...

Box 21 - £800, that helps too...

Box 10 - £35,000! I thought this was improving. Apparently not.

£200.01
50p
£1
£5
£50
£250
£6,750
£3,000
£10,000
£42,500
£142,500

Still have the "£150k" to play for of course... a good prediction here could leave you with only the -£11,000 as a big concern...

;_;
Um...
Let's try again?

PLAYER'S PREDICTION

£5,500

BANKER'S OFFER

£7,900

It's deja vu all over again.

BOX 25 MONEY MENU
15%
65%
115%
165%
215%
ADD CAR
-£11,000

At not-quite £8,000 this time, Deal or No Deal?

Really??
Either my calculator's stuffed up somewhere, or that's actually really generous. I'd need to brave the 50/50 of keeping the top two to get a significantly better offer (probably?), and I'd be in big trouble if I did hit one.
So... I think DEAL.
For proveout: 5, 2, 11; 16, 24, 17; 18, 23, 13; leaving 15 to the end.